Cytokeratin HMW, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Cytokeratin HMW, Human |
| Clone | REA914 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cytokeratin HMW Antibody, anti-human, APC, REAfinity™. Clone REA914 recognizes the human Cytokeratin HMW (High Molecular Weight), which includes the cytokeratins 1,5,10 and 14. Keratins are polypeptides with keratin-containing intermediate filaments, which play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions and are involved in intracellular signaling pathways. Clone REA914 detects squamous and ductal epithelium and other complex epithelia in normal tissues, e.g. basal cells in prostate, and myoepithelial cells in breast and corresponding tumors. | Additional information: Clone REA914 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 3848, 3852, 3858, 3861 |
| Catalog # | 130-115-261 |
| Price | $325 |
| Order / More Info | Cytokeratin HMW, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Moll, R. et al. (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31 (1): 11-24. | Yang, D. et al. (1999) Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286 (5439): 525-528. | Yang, X. J. et al. (1999) Rare expression of high-molecular-weight cytokeratin in adenocarcinoma of the prostate gland: a study of 100 cases of metastatic and locally advanced prostate cancer. Am J Surg Pathol 23 (2): 147-152. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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