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Antigenic Specificity | Mucin-2, Human |
Clone | REAL1317 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | allophycocyanin (APC) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mucin-2 Antibody, anti-human, APC, REAdye_lease™. Clone REAL1317 is an antibody fragment derived from the full Mucin-2 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1317 recognizes human Mucin-2, also known as MUC2, is an oligomeric mucus gel-forming glycoprotein secreted onto mucosal surfaces. It belongs to the mucin protein family, polymerizes into a gel and provides an insoluble mucous barrier that serves to protect the intestinal epithelium. Mucins may show aberrant expression, localization, and/or glycosylation in multiple malignancies. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogen | n/a |
Other Names | MUC-2, MUC2, SMUC, Intestinal mucin-2 |
Gene, Accession # | n/a |
Catalog # | 130-130-222 |
Price | $460 |
Order / More Info | Mucin-2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Pinto, R. et al. (2012) Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation. J. Cell. Mol. Med. 16 (7): 1474-1484. | Yamashita, M. S. A. et al. (2018) Mucin 2 (MUC2) promoter characterization: an overview. Cell Tissue Res. 374 (3): 455-463. | Astashchanka, A. et al. (2019) Mucin 2 (MUC2) modulates the aggressiveness of breast cancer. Genetics 173 (2): 289-299. |