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Antigenic Specificity | TCR Vβ6, Mouse |
Clone | REA884 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | APC-Vio 770 conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR Vβ6 Antibody, anti-mouse, APC-Vio® 770, REAfinity™. Clone REA884 recognizes the mouse V beta 6 T cell receptor (TCR Vβ6). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA884 recognizes TCR Vβ6 on mouse strains with the a (e.g., C57BR and SJL) and b haplotypes (e.g., BALB/c, C3H, and DBA/1). | Additional information: Clone REA884 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCR Vbeta6, TCR Vb6 |
Gene, Accession # | Gene ID: 100124662 |
Catalog # | 130-114-662 |
Price | $160 |
Order / More Info | TCR Vβ6, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Anderson, G. D. et al. (1989) MHC class II A alpha and E alpha molecules determine the clonal deletion of V beta 6+ T cells. Studies with recombinant and transgenic mice. J Immunol 143 (11): 3757-3761. | Rudy, C. K. et al. (1992) Mls-1-like superantigen in the MA/MyJ mouse is encoded by a new mammary tumor provirus that is distinct from Mtv-7. J. Exp. Med. 175 (6): 1613-1621. |