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Antigenic Specificity | CD102 (ICAM-2), Mouse |
Clone | REA745 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | Vio Bright B515 conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD102 (ICAM-2) Antibody, anti-mouse, Vio® Bright B515, REAfinity™. Clone REA745 recognizes the mouse CD102 antigen, also known as intercellular adhesion molecule 2 (ICAM-2). CD102 is a type I transmembrane glycoprotein belonging to the ICAM proteins of the Ig superfamily. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1. CD102 is found in endothelial cells and leukocytes and is expressed in high level in lung. CD102 plays a role in adhesive interactions, which are important for antigen-specific immune response, in NK-cell mediated clearance, and lymphocyte recirculation. Furthermore, CD102 is involved in other cellular interactions which are important for immune response and surveillance. | Additional information: Clone REA745 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | ICAM-2, ICAM2 |
Gene, Accession # | Gene ID: 15896 |
Catalog # | 130-130-164 |
Price | $199 |
Order / More Info | CD102 (ICAM-2), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Xu, H. et al. (1992) Isolation, characterization, and expression of mouse ICAM-2 complementary and genomic DNA. J Immunol 149 (8): 2650-2655. | Simmons, D. L. (1995) The role of ICAM expression in immunity and disease. Cancer Surv. 24: 144-155. | Casasnovas, J. M. et al. (1999) Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily. Proc. Natl. Acad. Sci. U.S.A. 96 (6): 3017-3022. |