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Antigenic Specificity | CD103, Human |
Clone | REA803 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | Vio Bright V423 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD103 Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA803 recognizes the human CD103 antigen, a type I transmembrane protein which is also known as αE integrin (ITGAE). It associates with integrin β7 to form the heterodimeric integrin molecule αEβ7 and is a receptor for the ligand E-cadherin expressed on epithelial cells. CD103 is found on intraepithelial and peripheral lymphocytes, such as regulatory T cell subpopulations. | Additional information: Clone REA803 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | ITGAE, HUMINAE, αE integrin, alpha E integrin, integrin alpha E |
Gene, Accession # | Gene ID: 3682 |
Catalog # | 130-127-386 |
Price | $208 |
Order / More Info | CD103, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Kruschwitz, M. et al. (1991) Ber-ACT8: New monoclonal antibody to the mucosa lymphocyte antigen. J Clin Pathol 44: 636-645. | Shaw, S. K. et al. (1994) Molecular cloning of the human mucosal lymphocyte integrin alpha E subunit. Unusual structure and restricted RNA distribution. J. Biol. Chem. 269 (8): 6016-6025. | Allakhverdi, Z. et al. (2006) Expression of CD103 identifies human regulatory T-cell subsets. J. Allergy Clin. Immunol. 118 (6): 1342-1349. |