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Antigenic Specificity | Ly-49F, Mouse |
Clone | REAL453 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | n/a |
Format | allophycocyanin (APC) conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ly-49F Antibody, anti-mouse, APC, REAlease®. Clone REAL453 is an antibody fragment derived from the full Ly-49F antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity. | Clone REA453 recognizes the mouse Ly-49F antigen (killer cell lectin-like receptor 6), a type II transmembrane natural killer (NK) cell receptor belonging to the Ly-49 family. Members of the Ly-49 family are homodimeric C-type lectin receptors, recognizing MHC class I molecules as ligands and include activating and inhibitory receptor molecules. The inhibitory receptor Ly-49F is expressed on subsets of NK cells, NK-T cells, and on a subpopulation of memory T cells in C57BL/6 mice, but not AKR/J, BALB/c, C3H/HeN, DBA/1, or SJL mice. IL-21 selectively down-regulates Ly-49F on mature NK cells. | The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes. |
Immunogen | n/a |
Other Names | Klra6, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F, Ly-49F |
Gene, Accession # | n/a |
Catalog # | 130-123-354 |
Price | $111 |
Order / More Info | Ly-49F, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | n/a |