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Antigenic Specificity | CD49b, Mouse/Rat |
Clone | REA981 |
Host Species | Recombinant Human |
Reactive Species | mouse, rat |
Isotype | IgG1 |
Format | PE-Vio 615 conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD49b Antibody, anti-mouse/rat, PE-Vio® 615, REAfinity™. Clone REA981 recognizes the mouse and rat CD49b antigen, a transmembrane glycoprotein also known as integrin alpha-2 (Itga2). CD49 is found on activated lymphocytes, epithelial cells, and platelets. In association with CD29 (integrin β-1), a VLA-2 complex is formed, which functions as a receptor for collagen and collagen C-propeptides, laminin, and E-cadherin. | Additional information: Clone REA981 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Integrin alpha-2, Itga2, Collagen receptor, intergrin α2 chain, VLA-2 α chain |
Gene, Accession # | Gene ID: 16398, 170921 |
Catalog # | 130-116-437 |
Price | $167 |
Order / More Info | CD49b, Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Hemler, M. E. et al. (1990) LA proteins in the integrin family: structures, functions, and their role on leukocytes. Annu. Rev. Immunol. 8: 365-400. | Wu, J. E. et al. (1994) Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Dev. Dyn. 199 (4): 292-314. |