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Antigenic Specificity | Claudin-3, Human |
Clone | REA751 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Claudin-3 Antibody, anti-human, APC, REAfinity™. Clone REA751 recognizes the human claudin-3 antigen, an integral membrane protein which is a component of the claudin family of epithelial tight junction proteins. Claudin-3 is involved in tight junction-specific obliteration of the intercellular space. It is a low-affinity receptor for Clostridium perfringens enterotoxinin (CPE). Binding of CPE to claudin-3 induces epithelial cell lysis. | Additional information: Clone REA751 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | CPE-R 2, hRVP1, CLDN3, C7orf1, CPETR2 |
Gene, Accession # | Gene ID: 1365 |
Catalog # | 130-110-835 |
Price | $142 |
Order / More Info | Claudin-3, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Morita, K. et al. (1999) Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Natl. Acad. Sci. U.S.A. 96 (2): 511-516. | Furuse, M. et al. (1999) Manner of interaction of heterogeneous claudin species within and between tight junction strands. J. Cell Biol. 147 (4): 891-903. | Coyne, C. B. et al. (2003) Role of claudin interactions in airway tight junctional permeability. Am. J. Physiol. Lung Cell Mol. Physiol. 285 (5): 1166-1178. |