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Antigenic Specificity | DO11.10 TCR, Mouse |
Clone | KJ1-26 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a |
Format | purified |
Size | 500 µg in 0.5 mL |
Concentration | n/a |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DO11.10 TCR Antibody, anti-mouse, pure-functional grade. The DO11.10 mouse model is a valuable tool for studies of T cell immigration, immunoregulation, development, activation, and function. The KJ1-26 monoclonal antibody reacts with the T cell receptor (TCR) expressed on lymphocytes of the DO11.10 transgenic mouse and the TCR of the BALB/c-derived DO11.10 and DO11.10.24 T cell hybridoma. The DO11.10 TCR is specific for the chicken ovalbumin (OVA) peptide (323-339) in the context of I-A[d] major histocompatibility (MHC) molecules. Transgenic DO11.10 T cells also recognize OVA peptide from jungle fowl and turkey in the presence of A20-1.11, the H-2d-bearing, antigen-presenting B cell lymphoma. |
Immunogen | n/a |
Other Names | TCRA, Tcralpha |
Gene, Accession # | Gene ID: 21473 |
Catalog # | 130-095-379 |
Price | $400 |
Order / More Info | DO11.10 TCR, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Haskins, K. et al. (1983) The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J. Exp. Med. 157 (4): 1149-1169. | Marrack, P. et al. (1983) The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J. Exp. Med. 158 (5): 1635-1646. | Murphy, K. M. et al. (1990) Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science 250 (4988): 1720-1723. |