CD35, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CD35, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD35, Human |
| Clone | REAL918 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD35 Antibody, anti-human, PE, REAdye_lease™. Clone REAL918 is an antibody fragment derived from the full CD35 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL918 recognizes the human cell surface protein CD35, the C3b/C4b receptor, also known as CR1 or complement receptor type I. CD35 belongs to the complement activation (RCA) family. Four CD35 allotypes with different molecular weights are known; 190, 220, 250 and 280 kDa. CD35 is expressed on hematopoietic cells such as granulocytes, monocytes, B cells, subsets of NK and T cells, erythrocytes, glomerular podocytes and follicular DCs. Known functions of CD35 include transport of C3 complexes on erythrocytes, complement activation, phagocytosis, and inhibition of the activation-induced proliferation of T and B cells. | CR1 has been associated with an increased risk of developing Alzheimer's disease. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
| Immunogen | n/a |
| Other Names | CR1, C3BR, C4BR, KN, C3b/C4b-R |
| Gene, Accession # | n/a |
| Catalog # | 130-127-121 |
| Price | $460 |
| Order / More Info | CD35, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Reilly, B. et al. (2010) Human peripheral CD4+ T-cells expressing complement receptor 1 (CR1, CD35). J Immunol 184 (1 Supplement): 138.3. | Reynes, M. et al. (1985) Human follicular dendritic cells express CR1, CR2, and CR3 complement receptor antigens. J Immunol 135: 2687-2694. | Klickstein, L. B. et al. (1988) Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis. J. Exp. Med. 168: 1699-1717. | Fonseca, M. I. et al. (2016) Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function. PLoS One 11 (2): . |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies