Cytokeratin 8/18, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Cytokeratin 8/18, Human |
| Clone | REAL1358 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cytokeratin 8/18 Antibody, anti-human, PE, REAdye_lease™. Clone REAL1358 is an antibody fragment derived from the full Cytokeratin 8/18 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1358 recognizes Cytokeratin 8 and Cytokeratin18, intermediate filament proteins that play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions and are involved in intracellular signaling pathways. Cytokeratin 8 and Cytokeratin18 copolymerizes to form a component of the cytoskeleton to differentiate cells of epithelial origin from hematopoietic cells and to enumerate circulating tumor cells in blood. Cytoceratin 8/18 are expressed in epithelia cells and many epithelial cell derived cancers. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | Keratin, type I cytoskeletal 18, KRT18, Cytokeratin-18, CK-18, Keratin, type II cytoskeletal 8, KRT8, Cytokeratin-8, CK-8, CYK18, CYK8 |
| Gene, Accession # | n/a |
| Catalog # | 130-131-849 |
| Price | $510 |
| Order / More Info | Cytokeratin 8/18, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Mohanty, S. K. et al. (2015) BRCA-mutated Invasive Breast Carcinomas: Immunohistochemical Analysis of Insulin-like Growth Factor II mRNA-binding Protein (IMP3), Cytokeratin 8/18, and Cytokeratin 14. 21 (6): 596-603. | Lim, J. et al. (2021) Revealing the Roles of Keratin 8/18-Associated Signaling Proteins Involved in the Development of Hepatocellular Carcinoma. Int J Med Sci. 22 (12): 6401. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG