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Antigenic Specificity | CD102 (ICAM-2), Human |
Clone | REA878 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD102 (ICAM-2) Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA878 recognizes the human CD102 antigen, a type I transmembrane glycoprotein with two immunoglobulin-like domains. CD102, also known as ICAM-2, is a member of the intercellular adhesion molecule (ICAM) family, that binds to leukocyte integrin, lymphocyte function-associated antigen-1 (LFA-1), dendritic cell-specific antigen, ICAM-grabbing non-integrin (DC-SIGN) protein and macrophage-1 antigen (MAC-1). CD102 is found on vascular endothelial cells, monocytes, platelets and different populations of lymphocytes. | CD102 is involved in lymphocyte recirculation and induces essential adhesive cell interactions, which are important for immune response and surveillance. | Additional information: Clone REA878 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | ICAM-2 |
Gene, Accession # | Gene ID: 3384 |
Catalog # | 130-114-413 |
Price | $170 |
Order / More Info | CD102 (ICAM-2), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Staunton, D. E. et al. (1989) Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature 339 (6219): 61-64. | Simmons, D. L. (1995) The role of ICAM expression in immunity and disease. Cancer Surv. 24: 144-155. | Weber, K. S. et al. (2004) Sialylation of ICAM-2 on platelets impairs adhesion of leukocytes via LFA-1 and DC-SIGN. Inflammation 28 (4): 177-188. |