SPARC, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | SPARC, Human |
| Clone | REAL1146 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SPARC Antibody, anti-human, FITC, REAdye_lease™. Clone REAL1146 is an antibody fragment derived from the full SPARC antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL1146 recognizes SPARC, a 43kDa cysteine-rich acidic matrix-associated protein, which is also known as Osteonectin and ON. It is mainly detected in the extracellular compartment. SPARC has different functions. It plays a role in cell differentiation, proliferation and angiogenesis and is involved in tissue remodeling and wound repair. Expression of SPARC is detected in different tissues and organs and has been associated with tumor suppression. A strong expression is found in tissues undergoing morphogenesis and wound repair. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
| Immunogen | n/a |
| Other Names | Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine |
| Gene, Accession # | n/a |
| Catalog # | 130-129-890 |
| Price | $385 |
| Order / More Info | SPARC, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Feng, J. et al. (2014) SPARC in Tumor Pathophysiology and as a Potential Therapeutic Target. Curr. Pharm. Des. 20 (39): 6182-6190. | Rosset, E. M. and Bradshaw, A. D. et al. (2016) SPARC/osteonectin in mineralized tissue. Matrix Biol. 52 (54): 78-87. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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