ESAM, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | ESAM, Mouse |
| Clone | REA722 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ESAM Antibody, anti-mouse, APC, REAfinity™. Clone REA722 recognizes the mouse endothelial cell-selective adhesion molecule (ESAM) antigen, a 55 kDa molecule, which is also known as a transmembrane tight junction protein composed of a single transmembrane domain and a cytoplasmic domain. By affecting endothelial cell contacts, ESAM is mostly expressed on endothelial cells of various organs such as heart, lung, kidney, and skin, participating in the migration of neutrophils through the vessel wall. | Additional information: Clone REA722 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | Endothelial cell-selective adhesion molecule, ESAM1 |
| Gene, Accession # | Gene ID: 69524 |
| Catalog # | 130-111-277 |
| Price | $365 |
| Order / More Info | ESAM, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Hirata, K. et al. (2001) Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells. J. Biol. Chem. 276 (19): 16223-16231. | Nasdala, I. et al. (2002) A transmembrane tight junction protein selectively expressed on endothelial cells and platelets. J. Biol. Chem. 277 (18): 16294-16303. | Wegmann, F. et al. (2004) Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contacts. Exp. Cell Res. 300 (1): 121-133. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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