CD318 (CDCP1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD318 (CDCP1), Human |
| Clone | REA194 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PerCP-Vio 700 conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD318 (CDCP1) Antibody, anti-human, PerCP-Vio® 700, REAfinity™. Clone REA194 recognizes CD318, a type I transmembrane protein which is also known as CUB domain-containing protein 1 (CDCP1) or SIMA135. CD318 has an approximate molecular weight of 93 kDa and contains an extracellular domain with three regions with low homology to complement protein subcomponents C1r/C1s, urchin embryonic growth factor, and bone morphogenetic protein 1 (CUB) domains. CD318 has been suggested to be an interacting partner of Src family kinase and protein kinase Cδ. It has been shown that CD318 plays a role in cancer progression and the development of metastases. CD318 expression is found widely in normal tissues, whereas an aberrant overexpression is suggested to be associated with tumor cells. | Additional information: Clone REA194 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | CDCP1, SIMA135, TRASK |
| Gene, Accession # | Gene ID: 64866 |
| Catalog # | 130-101-220 |
| Price | $151 |
| Order / More Info | CD318 (CDCP1), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Liu, H. et al. (2011) CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis. Proc. Natl. Acad. Sci. U.S.A. 108: 1379-1384. | Conze, T. et al. (2003) CDCP1 is a novel marker for hematopoietic stem cells. Ann. N. Y. Acad. Sci. 996: 222-226. | Scherl-Mostageer, M. et al. (2001) Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. Oncogene 20 (32): 4402-4408. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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