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Antigenic Specificity | Cytokeratin 5/6, Human |
Clone | REA913 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 200 µL |
Concentration | 1:50 |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytokeratin 5/6 Antibody, anti-human, PE, REAfinity™. Clone REA913 recognizes the human Cytokeratin 5/6, belonging to the basic or neutral type II cytokeratins. Cytokeratins, which are found in almost all epithelial cells, are polypeptides with keratin-containing intermediate filaments, which ensure form stability and cohesiveness. Cytokeratin 6 is located in proliferating squamous epithelium, whereas Cytokeratin 5 is found in the basal, the intermediate and the superficial cell layers of stratified and transitional epithelia, complex epithelia, and in mesothelial cells and mesothelioma, but not in simple epithelia and in non-epithelial cells. | Additional information: Clone REA913 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | KRT5, K5, Keratin-5, KRT5A, Cytokeratin-5, CK5, CK-5 |
Gene, Accession # | Gene ID: 3852, 3853, 3854 |
Catalog # | 130-115-257 |
Price | $315 |
Order / More Info | Cytokeratin 5/6, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Moll, R. et al. (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31 (1): 11-24. | Lersch, R. et al. (1988) Sequence and expression of a type II keratin, K5, in human epidermal cells. Mol. Cell. Biol. 8 (1): 486-493. |