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Antigenic Specificity | EPHB4, Human |
Clone | REA923 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EPHB4 Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA923 recognizes the human ephrin type-B receptor 4 (EPHB4) antigen, which is a member of the Eph receptor tyrosine kinase family. The ligand for EPHB4 is ephrin-B2. EPHB4 is found in different tissues, e.g., in placenta, kidney, liver, lung, pancreas, skeletal muscle, and heart. It is expressed on myeloid hematopoietic cells and endothelial cells. EPHB4 functions as an inhibitor for cell-cell adhesion, chemotaxis, and angiogenesis as well as a promoter for the differentiation of megakaryocytic and erythroid progenitor cells. | Additional information: Clone REA923 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | Ephrin type-B receptor 4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11, HTK, MYK1, TYRO11 |
Gene, Accession # | Gene ID: 2050 |
Catalog # | 130-115-501 |
Price | $365 |
Order / More Info | EPHB4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Erber, R. et al. (2006) EphB4 controls blood vascular morphogenesis during postnatal angiogenesis. EMBO J. 25 (3): 628-641. | Fuller, T. et al. (2003) Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells. J. Cell. Sci. 116 (12): 2461-2470. |