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Antigenic Specificity | TCR Vα2, Mouse |
Clone | REA679 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | VioBlue conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR Vα2 Antibody, anti-mouse, VioBlue®, REAfinity™. Clone REA679 recognizes the mouse Vα2 T cell receptor (TCR Vα2) of mice having the a, b, and c haplotypes. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vα elements are expressed preferentially in CD4 or CD8 subsets in a manner that is largely independent of the MHC haplotype. It is likely that the Vα elements interact preferentially with conserved regions of class I or class II molecules. | Additional information: Clone REA679 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCR Va2, TCR alpha2 |
Gene, Accession # | Gene ID: 100042372 |
Catalog # | 130-110-301 |
Price | $140 |
Order / More Info | TCR Vα2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Kubo, R. T. et al. (1989) Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. J Immunol 142 (8): 2736-2742. | Gregoire, C. et al. (1991) Engineered secreted T-cell receptor alpha beta heterodimers. Proc. Natl. Acad. Sci. U.S.A. 88 (18): 8077-8081. |