Notch4, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Notch4, Mouse |
| Clone | HMN4-14 |
| Host Species | Hamster |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Notch4 Antibody, anti-mouse, APC. The HMN4-14 monoclonal antibody reacts with mouse Notch4, one of four members of the Notch family of receptors. Upon binding its membrane-bound ligand of the Delta-like or Jagged family members, the Notch receptor undergoes two proteolytic cleavage steps eventually releasing the Notch intracellular domain (NICD), which subsequently translocates into the nucleus, where it activates transcription within a multi-protein complex. Notch4 is preferentially expressed by endothelial cells, e.g., vascular smooth muscle cells and is reported to play a critical role in vasculogenesis and angiogenesis. It is also expressed on various other cell types including hematopetic cells. In addition, the altered expression of Notch4 by various leukemias, lymphomas, and cancers has been reported. |
| Immunogen | n/a |
| Other Names | Int-3, Int3, N4 |
| Gene, Accession # | Gene ID: 18132 |
| Catalog # | 130-102-309 |
| Price | $89 |
| Order / More Info | Notch4, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | n/a |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG