DO11.10 TCR, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityDO11.10 TCR, Mouse
CloneKJ1-26
Host SpeciesMouse
Reactive Speciesmouse
IsotypeIgG2aκ
FormatVioBlue conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionDO11.10 TCR Antibody, anti-mouse, VioBlue®. The DO11.10 mouse model is a valuable tool for studies of T cell immigration, immunoregulation, development, activation, and function. The KJ1-26 monoclonal antibody reacts with the T cell receptor (TCR) expressed on lymphocytes of the DO11.10 transgenic mouse and the TCR of the BALB/c-derived DO11.10 and DO11.10.24 T cell hybridoma. The DO11.10 TCR is specific for the chicken ovalbumin (OVA) peptide (323-339) in the context of I-A[d] major histocompatibility (MHC) molecules. Transgenic DO11.10 T cells also recognize OVA peptide from jungle fowl and turkey in the presence of A20-1.11, the H-2d-bearing, antigen-presenting B cell lymphoma.
Immunogenn/a
Other NamesTCRA, Tcralpha
Gene, Accession #Gene ID: 21473
Catalog #130-102-136
Price$136
Order / More InfoDO11.10 TCR, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesHaskins, K. et al. (1983) The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J. Exp. Med. 157 (4): 1149-1169. | Marrack, P. et al. (1983) The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity. J. Exp. Med. 158 (5): 1635-1646. | Murphy, K. M. et al. (1990) Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science 250 (4988): 1720-1723.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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