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Antigenic Specificity | GBL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GBL Antibody: GbetaL (G protein beta protein subunit-like) is a member of a signaling pathway that regulates mammalian cell growth in response to the presence of nutrients and growth factors. It binds to the kinase domain of TOR (Target of rapamycin, also known as mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. Rapamycin inhibits TOR resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. TOR is normally associated with GbetaL and an additional regulatory protein RAPTOR, allowing TOR to control protein biosynthesis. The binding of GbetaL to TOR stimulates TOR's kinase activit |
Immunogen | Immunogen: GbL antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human GbL. Buffer: GBL Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [GBL; GBL; LST8; POP3; WAT1; GbetaL; GBL; Target of rapamycin complex subunit LST8; G protein beta subunit-like; TORC subunit LST8; G protein beta subunit-like], [MLST8; MLST8; GBL; LST8; POP3; WAT1; GbetaL; GBL; LST8; TORC subunit LST8; Gable; Protein GbetaL; mLST8] |
Gene, Accession # | [MLST8], Gene ID: 64223, NCBI: AAH52292, UniProt: Q9BVC4 |
Catalog # | MBS150146 |
Price | $375 |
Order / More Info | GBL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |