Edit |   |
Antigenic Specificity | Yes1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Yes(YES1) detection. Tested with WB, IHC-P in Human. Background: Proto-oncogene tyrosine-protein kinase Yes is an enzyme that in humans is encoded by the YES1 gene. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. YES1 has been shown to interact with Janus kinase 2, CTNND1, RPL10 and Occludin. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Yes1 (7-35aa KENKSPAIKYRPENTPEPVSTSVSHYGAE), different from the related mouse sequence by six amino acids, and from the related rat sequence by seven amino acids. Ig Type: Rabbit IgG |
Other Names | [Tyrosine-protein kinase Yes; c Yes; Cellular Yes 1 protein; Cellular Yes1 protein; HsT441; P61 YES; p61-Yes; Proto oncogene tyrosine protein kinase YES; Proto-oncogene c-Yes; Proto-oncogene tyrosine-protein kinase Yes; Tyrosine-protein kinase Yes; v yes 1 Yamaguchi sarcoma viral oncogene homolog 1; Viral oncogene yes 1 homolog 1; Viral oncogene yes1 homolog 1; Yamaguchi sarcoma oncogene; Yes 1; Yes; YES_HUMAN; YES1; YES proto-oncogene 1, Src family tyrosine kinase], [YES1; YES1; Yes; c-yes; HsT441; P61-YES; YES] |
Gene, Accession # | [YES1], Gene ID: 7525, NCBI: NP_005424.1, UniProt: P07947 |
Catalog # | MBS178302 |
Price | $315 |
Order / More Info | Yes1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 2. Chen, Yan-Hua; Lu Qun; Goodenough Daniel A; Jeansonne Beverly (Apr 2002).Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells. Mol. Biol. Cell (United States) 13 (4): 1227-37. |