c-Abl Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | c-Abl |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes c-Abl protein. It cross react to human and mouse. The other species was not tested. The c-Abl proto-oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. It is activated by certain DNA-damaging agents and regulates induction of the stress-activated c-Jun N-terminal protein kinase (SAPK). In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c-Abl proto-oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c-Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric |
| Immunogen | n/a |
| Other Names | [c-abl oncogene 1, non-receptor tyrosine kinase], [ABL1; ABL1; ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl; ABL; JTK7] |
| Gene, Accession # | [c-Abl], Gene ID: 25, NCBI: AAA51896.1 |
| Catalog # | MBS460250 |
| Price | $285 |
| Order / More Info | c-Abl Antibody from MYBIOSOURCE INC. |
| Product Specific References | Surender Kharbanda, et al. Activation of MEK Kinase 1 by the c-Abl Protein Tyrosine Kinase in Response to DNA Damage Molecular and Cellular Biology, 20 (14), 4979-4989 (2000) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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