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Antigenic Specificity | BICD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of BICD1 are known to exist; this antibody will only recognize the larger isoform. BICD1 Antibody: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved i |
Immunogen | Immunogen: BICD1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BICD1. Buffer: BICD1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [BICD1; BICD; Protein bicaudal D homolog 1; Bic-D 1; bicaudal D homolog 1 (Drosophila)], [BICD1; BICD1; BICD; Bic-D 1] |
Gene, Accession # | [BICD1], Gene ID: 636, NCBI: NP_001705, UniProt: Q96G01 |
Catalog # | MBS150672 |
Price | $375 |
Order / More Info | BICD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |