Edit |   |
---|---|
Antigenic Specificity | RBM35A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RBM35A antibody is predicted to not cross-react with other RBM35/ESRP family members. At least five isoforms of RBM35A are known to exist; this antibody will detect all five. RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 18 amino acid peptide near the amino terminus of human RBM35A. |
Other Names | [RNA-binding motif protein 35A, RMB35A, Epithelial splicing regulatory protein 1, ESRP1] |
Gene, Accession # | [RBM35A], Gene ID: 54845, NCBI: NP_001030087 |
Catalog # | MBS9404383 |
Price | $320 |
Order / More Info | RBM35A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |