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Antigenic Specificity | MEKK1 (C-term), 1145-1176 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 1.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MEKK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1145-1176 amino acids from the C-terminal region of human MEKK1. Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK1 can phosphorylate and activate MAPKK 1 and MAPKK 2 (MEK1/MEK2) which leads to phosphorylation of MAP kinases. It is also a highly efficient |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1; MAP3K1; MAPKKK1; MEKK; MEKK1] |
Gene, Accession # | [MAP3K1], Gene ID: 4214, NCBI: NP_005912.1, UniProt: Q13233 |
Catalog # | MBS9201796 |
Price | $165, $370 |
Order / More Info | MEKK1 (C-term), 1145-1176 Antibody from MYBIOSOURCE INC. |
Product Specific References | Xia, Y., et al., Genes Dev. 12(21):3369-3381 (1998). Vinik, B.S., et al., Mamm. Genome 6(11):782-783 (1995). |