Human ADAM-10 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman ADAM-10
Clone[6D39]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe monoclonal antibody reacts with human CD156c, which is also known as a disintegrin and metalloproteinase domain-containing protein (ADAM) 10. This type I transmembrane glycoprotein is expressed ubiquitously on hematopoietic and non-hematopoietic cell types. Studies demonstrate that CD156c expression is regulated by PAX2 in cancer cells. CD156c plays a critical role in hematopoiesis, including lymphocyte development, and autoimmunity by regulating the shedding and secretion of various receptors and chemokines, including Notch, CD23, CXCL16, and the IL-6R. Finally, deregulated CD156c expression has been associated with T-cell acute lymphoblastic lymphoma (T-ALL) and Alzheimer's disease.
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human ADAM-10 (extracellular domain) recombinant protein.
Other Names[ADAM10; kuz; AD10; MADM; CD156c; HsT18717], [ADAM10; ADAM10; RAK; kuz; AD10; AD18; MADM; CD156c; HsT18717; KUZ; MADM; ADAM 10]
Gene, Accession #[ADAM-10], Gene ID: 102, NCBI: NP_001101.1, UniProt: O14672
Catalog #MBS690006
Price$475
Order / More InfoHuman ADAM-10 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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