Caspase-3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Caspase-3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP) (1). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position (2). |
| Immunogen | Immunogen: Recombinant protein of human CASP3 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CPP32; CPP32B; SCA-1; Caspase-3; APOPAIN] |
| Gene, Accession # | [CASP3], Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574 |
| Catalog # | MBS8502699 |
| Price | $310 |
| Order / More Info | Caspase-3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Fernandes-Alnemri, T. et al. (1994) J. Biol. Chem. 269, 30761-30764. 2. Nicholson, D. W. et al. (1995) Nature 376, 37-43. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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