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Antigenic Specificity | SKAP1 (C-term), 266-295 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SKAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the C-terminal region of human SKAP1. This gene encodes a T cell adaptor protein, a class ofintracellular molecules with modular domains capable of recruitingadditional proteins but that exhibit no intrinsic enzymaticactivity. The encoded protein contains a unique N-terminal regionfollowed by a PH domain and C-terminal SH3 domain. Along with theadhesion and degranulation-promoting adaptor protein, the encodedprotein plays a critical role in inside-out signaling by couplingT-cell antigen receptor stimulation to the activation of integrins. |
Immunogen | n/a |
Other Names | [Src kinase-associated phosphoprotein 1; Src family-associated phosphoprotein 1; Src kinase-associated phosphoprotein of 55 kDa; SKAP-55; pp55; SKAP1; SCAP1; SKAP55] |
Gene, Accession # | [SKAP1], Gene ID: 8631, NCBI: NP_001068567.1, UniProt: Q86WV1 |
Catalog # | MBS9201190 |
Price | $165, $370 |
Order / More Info | SKAP1 (C-term), 266-295 Antibody from MYBIOSOURCE INC. |
Product Specific References | Goode, E.L., et al. Nat. Genet. 42(10):874-879(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Raab, M., et al. Immunity 32(4):541-556(2010) Lehmann, R., et al. Proteomics 9(23):5288-5295(2009) Fang, L., et al. Cell Cycle 8(17):2819-2827(2009) |