Human E3 ubiquitin-protein ligase parkin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human E3 ubiquitin-protein ligase parkin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | caprylic acid ammonium sulfate precipitate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM20, USP30, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or detoxification of abnormally folded or damaged protein by mediating 'Lys-63'-linked polyubiquitination of misfolded proteins such as PARK7: 'Lys-63'-linked polyubiquitinated misfolded proteins are then recognized by HDAC6, leading to their recruitment to aggresomes, followed by de |
| Immunogen | Immunogen: Recombinant human E3 ubiquitin-protein ligase parkin protein(1-465AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-31601 / sc-13279 / sc-31603 / sc-30130 |
| Other Names | [Parkinson juvenile disease protein 2; Parkinson disease protein 2; PRKN; PARK2], [PARK2; PARK2; PDJ; PRKN; AR-JP; LPRS2; PRKN; Parkin; Parkinson disease protein 2] |
| Gene, Accession # | Gene ID: 5071, NCBI: NP_004553.2, UniProt: O60260 |
| Catalog # | MBS968850 |
| Price | $160, $235 |
| Order / More Info | Human E3 ubiquitin-protein ligase parkin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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