Human Receptor tyrosine-protein kinase ErbB-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Receptor tyrosine-protein kinase ErbB-1 |
| Clone | [DP-4A1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), CELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human Receptor tyrosine-protein kinase ErbB-1 (EGFR). Background: Epidermal growth factor receptor (EGFR; ErbB-1) is a 170-kDa transmembrane glycoprotein encoded by the HER1 proto-oncogene. It belongs to the EGFR family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her3 (ErbB-3) and Her4 (ErbB-4). ErbB-1 is expressed on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor ? (TGF?). Growth factor binding to the extracellular domain of ErbB-1 induces formation of homoand heterodimers with another member of the ErbB receptor family. The EGFR signaling pathway is one of the most i |
| Immunogen | Immunogen: Immunogen: cDNA |
| Other Names | [EGFR], [EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB; ERBB1; HER1] |
| Gene, Accession # | Gene ID: 1956, NCBI: NP_005219.2, UniProt: P00533 |
| Catalog # | MBS468037 |
| Price | $505 |
| Order / More Info | Human Receptor tyrosine-protein kinase ErbB-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Normanno N, Bianco C, Strizzi L, Mancino M, Maiello MR, De Luca A, Caponigro F andSalomon DS (2005). The ErbB receptors and their ligands in cancer: an overview. Curr DrugTargets 6(3):243-57Harari PM (2004). Epidermal growth factor receptor inhibition strategies in oncology. EndocrRelat Cancer. 11(4):689-708 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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