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Antigenic Specificity | von Willebrand Factor/Factor VIII Related-Ag (Endothelial Marker) |
Clone | [VWF/1465] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial different |
Immunogen | Immunogen: Recombinant fragment of human vWF protein (aa1815-1939) Cellular Localization: Cytoplasmic |
Other Names | [Coagulation Factor VIII; Factor VIII Related Antigen; F8VWF; von Willebrand Antigen 2; von Willebrand Disease (vWD)] |
Gene, Accession # | [VWF], Gene ID: 7450, NCBI: NP_000543.2, UniProt: P04275 |
Catalog # | MBS4380282 |
Price | $190, $340, $340 |
Order / More Info | von Willebrand Factor/Factor VIII Related-Ag (Endothelial Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Motta, A. et al. 2009. J Biomater Sci Polym Ed. 20: 1875-1897. Germann, B. et al. 2008. Pharmazie. 63: 303-307. |