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Antigenic Specificity | NR2C1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total NR2C1 polyclonal antibody. Orphan nuclear receptor.Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes.Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation.Mediator of retinoic acid-regulated preadipocyte proliferation. |
Immunogen | Immunogen: Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein(1-240aa) |
Other Names | [Orphan nuclear receptor TR2; Testicular receptor 2; NR2C1; TR2] |
Gene, Accession # | [NR2C1], Gene ID: 7181, NCBI: NP_001027458.1, UniProt: P13056 |
Catalog # | MBS9416432 |
Price | $320 |
Order / More Info | NR2C1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |