Mouse PDGFR-beta Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse PDGFR-beta |
| Clone | [4C54] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) - Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background/Introduction: The platelet-derived growth factor (PDGF) family consists of proteins derived from four genes (PDGF-A, B, C, and D) that form disulfidelinked homodimers (PDGF-AA, BB, CC, and DD) and a heterodimer (PDGF-AB). These proteins regulate diverse cellular functions by binding to and inducing the homo- or heterodimerization of two receptors (PDGF Ralpha and Rbeta). Whereas alpha/alpha homodimerization is induced by PDGF-AA, BB, CC, and AB, alpha/beta heterodimerization is induced by PDGF-AB, -BB, CC, and DD, and beta/beta homodimerization is induced only by PDGF-BB, and DD. Both PDGF-Ralpha and -Rbeta are members of the class III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for MCSF, SCF and |
| Immunogen | Preparation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with purified mouse PDGF receptor - beta extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein G affinity hromatography. Antigen: Recombinant mouse PDGFR beta extracellular domain. Reconstitution buffer: PBS (sterile). |
| Other Names | [mouse PDGF receptor-beta], [Pdgfrb; Pdgfrb; Pdgfr; CD140b; PDGFR-1; AI528809; Pdgfr; Pdgfr1; PDGF-R-beta; PDGFR-beta; PDGFR-1] |
| Gene, Accession # | [PDGFR-beta], Gene ID: 18596, NCBI: NP_001139740.1, UniProt: P05622 |
| Catalog # | MBS690560 |
| Price | $490 |
| Order / More Info | Mouse PDGFR-beta Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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