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Antigenic Specificity | AP3B1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AP3B1 antibody detects endogenous levels of AP3B1. Function: Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.Subunit Structure: AP-3 assoc |
Immunogen | Immunogen: A synthesized peptide derived from human AP3B1. Subcellular Location: Golgi Apparatus. Cytoplasmic Vesicle > Clathrin-Coated Vesicle Membrane. Golgi Apparatus. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. Tissue Specificity: Ubiquitously expressed. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100% |
Other Names | [Adapter related protein complex 3 beta 1 subunit; Adapter-related protein complex 3 subunit beta-1; Adaptor protein complex AP-3 subunit beta-1; Adaptor protein complex AP3 beta1 subunit; ADTB3; ADTB3A; AP-3 complex subunit beta-1; AP3 complex beta1 subunit; AP3B1; AP3B1_HUMAN; Beta-3A-adaptin; Beta3A adaptin; Clathrin assembly protein complex 3 beta 1 large chain; Clathrin assembly protein complex 3 beta-1 large chain; HPS; PE] |
Gene, Accession # | [AP3B1], Gene ID: 8546, NCBI: NP_001258698.1, UniProt: O00203 |
Catalog # | MBS9603320 |
Price | $240, $280 |
Order / More Info | AP3B1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |