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Antigenic Specificity | IL27 |
Clone | [1354] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-27, a member of IL-12/IL-23 heterodimeric family of cytokines, has pleiotropic properties that can enhance or limit immune responses. IL-27 is a heterodimeric cytokine composed of two subunits: IL-27a and IL-27b. IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various huma |
Immunogen | Immunogen: Fusion protein of IL-27 |
Other Names | [EBI3; IL 27; IL 27 p28 subunit; IL 27A; IL 30; IL-27 subunit alpha; IL-27-A; IL27; IL27-A; IL27A; IL27A; IL27p28; IL30; Interleukin 27; Interleukin 27 subunit alpha; Interleukin 27; 28-KD subunit; Interleukin 30; Interleukin-27 subunit alpha; p28] |
Gene, Accession # | [IL27], Gene ID: 246778, NCBI: NP_663634.2, UniProt: Q8NEV9 |
Catalog # | MBS2542258 |
Price | $220, $290, $435 |
Order / More Info | IL27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |