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Antigenic Specificity | TUCAN / CARD8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.2 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: TUCAN (Tumor Up-regulated Card-containing Antagonist of Caspase-Nine) is a CARD (Caspase-Associated Recruitment Domains) containing protein that binds and suppresses activation of pro-Caspase-9 and found to be overexpressed in some types of cancers. TUCAN binds specifically to pro-caspase-9 and interferes with its interaction with Apaf-1, thereby suppressing apoptosis signaling in the mitochondrial/cytochrome c pathway. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 420 of human TUCAN |
Other Names | [DACAR; NDPP1; TUCAN; CARDINAL; KIAA0955; MGC57162; DKFZp779L0366], [CARD8; CARD8; NDPP; DACAR; DAKAR; NDPP1; TUCAN; CARDINAL; KIAA0955; NDPP1; CARDINAL; TUCAN] |
Gene, Accession # | [TUCAN/CARD8], Gene ID: 22900, NCBI: NP_001171829.1, UniProt: Q9Y2G2 |
Catalog # | MBS841244 |
Price | $150, $290 |
Order / More Info | TUCAN / CARD8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |