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Antigenic Specificity | Keratin 8 (Phospho-Ser74) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of Keratin 8 only when phosphorylated at serine 74. Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8). |
Other Names | [CK 8; CK8; CYK8; Cytokeratin endo A; K8] |
Gene, Accession # | Gene ID: 3856, NCBI: NP_001243222.1, UniProt: P05787 |
Catalog # | MBS9403387 |
Price | $200, $255 |
Order / More Info | Keratin 8 (Phospho-Ser74) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |