Keratin 8 (Phospho-Ser74) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKeratin 8 (Phospho-Ser74)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous level of Keratin 8 only when phosphorylated at serine 74. Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8).
Other Names[CK 8; CK8; CYK8; Cytokeratin endo A; K8]
Gene, Accession #Gene ID: 3856, NCBI: NP_001243222.1, UniProt: P05787
Catalog #MBS9403387
Price$200, $255
Order / More InfoKeratin 8 (Phospho-Ser74) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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