hnRNP C1/C2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | hnRNP C1/C2 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed: 8264621). Specifically recognizes and binds N6- methyladenosine (m6A)-containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non- coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch' to facilitate binding of HNRNPC, leading to regulation of mRNA splicing (PubMed: 25719671). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre- mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'- UTR of mRNA and modulates the stability and the |
| Immunogen | Immunogen: A synthesized peptide derived from human hnRNP C1/C2. Subcellular Localization: Nucleus. Component of ribonucleosomes. |
| Other Names | [Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; HNRNPC; HNRPC], [HNRNPC; HNRNPC; C1; C2; HNRNP; HNRPC; SNRPC; HNRPC; hnRNP C1/C2] |
| Gene, Accession # | [HNRNPC], Gene ID: 3183, NCBI: NP_001070910.1, UniProt: P07910 |
| Catalog # | MBS179886 |
| Price | $160, $340, $340 |
| Order / More Info | hnRNP C1/C2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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