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Antigenic Specificity | MAPK3/1 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have alr |
Immunogen | Immunogen: This MAPK3/1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 195-228 amino acids from the central region of human MAPK3/1. |
Other Names | [ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MAPK3] |
Gene, Accession # | [MAPK3/1], Gene ID: 5595, NCBI: NP_001035145.1, UniProt: P27361 |
Catalog # | MBS8558810 |
Price | $280 |
Order / More Info | MAPK3/1 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |