PAR1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPAR1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: PAR1 antibody detects endogenous levels of total PAR1. Function: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.Post-translational Modifications: A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. Phosphorylated in the C-terminal tail; probably mediating desensitization prior to the uncoupling and internalization of the receptor.Similarity: The cleaved signal peptide may not be degraded and may function as an intracellular angiogenesis inhibitor peptide known as parstatin. Belongs to the G-protein coupled receptor 1 family.
ImmunogenImmunogen: Purified recombinant fragment of human PAR1 expressed in E. Coli Subcellular Location: Cell Membrane Tissue Specificity: Platelets and vascular endothelial cells.
Other Names[CF2R; Coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR 1; PAR-1; PAR1; PAR1_HUMAN; Protease activated receptor 1; Proteinase activated receptor 1; Proteinase-activated receptor 1; Thrombin receptor; TR]
Gene, Accession #[PAR1], Gene ID: 2149, NCBI: NP_001298242.1, UniProt: P25116
Catalog #MBS9602651
Price$235, $295, $370
Order / More InfoPAR1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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