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Antigenic Specificity | HDAC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008] |
Immunogen | Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human HDAC1 around the phosphorylation site of serine 421/423. Sensitivity: This antibody detects endogenous levels of HDAC1 and does not cross-react with related proteins. Sequence Similarities: Belongs to the histone deacetylase family. HD type 1 subfamily. |
Other Names | [DKFZp686H12203; GON 10; HD 1; HD1; HDAC 1; HDAC1; hdac1: histone deacetylase 1; HDAC1_HUMAN; Histone deacetylase 1 (HD1); Histone deacetylase 1; Reduced potassium dependency yeast homolog like 1; RPD3 (reduced potassium dependency yeast homolog) like 1; RPD3 (reduced potassium dependency); RPD3; RPD3L1], [HD1; RPD3; GON-10; RPD3L1] |
Gene, Accession # | [HDAC1], Gene ID: 3065, NCBI: NP_004955.2, UniProt: Q13547 |
Catalog # | MBS477133 |
Price | $335 |
Order / More Info | HDAC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |