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Antigenic Specificity | CTNNA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may |
Immunogen | Immunogen: Recombinant human Catenin alpha-1 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1495 / sc-7894 |
Other Names | [Catenin alpha-1; CTNNA1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13], [CTNNA1; CTNNA1; CAP102] |
Gene, Accession # | [CTNNA1], Gene ID: 1495, NCBI: NP_001277236.1, UniProt: P35221 |
Catalog # | MBS1492403 |
Price | $160, $235 |
Order / More Info | CTNNA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |