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Antigenic Specificity | CHEK2/CHK2 |
Clone | [4B7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human Chk2. Serine/threonine-protein kinase which is required forcheckpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-str and breaks. Mayalso negatively regulate cell cycle progression during unperturbed cellcycles. Following activation, phosphorylates numerous effectorspreferentially at the consensus sequence [L-X-R-X-X-S/T]. |
Immunogen | Immunogen: CHEK2 (AAH04207, 1 a.a. ~ 544 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated |
Other Names | [Rabbit (IgG) to Human CHEK2/CHK2; CHEK2; BA444G7; Cds1 homolog; Checkpoint kinase 2; Checkpoint-like protein CHK2; CHK2 checkpoint homolog; CHK2; HCds1; LFS2; RAD53; Rad53 homolog; HCHK2; HuCds1; PP1425] |
Gene, Accession # | [CHEK2/CHK2], Gene ID: 11200, NCBI: NP_009125.1, UniProt: O96017 |
Catalog # | MBS2400645 |
Price | $605 |
Order / More Info | CHEK2/CHK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |