Cortactin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cortactin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Cortactin Polyclonal Antibody detects endogenous levels of Cortactin protein. CTTN is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The cortactin is localized in the cytoplasm and in areas of the cell-substratum contacts. CTTN has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. |
| Immunogen | Immunogen: Synthesized peptide derived from human Cortactin around the non-phosphorylation site of Y446 |
| Other Names | [Rabbit Cortactin; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1] |
| Gene, Accession # | [CTTN], Gene ID: 2017, NCBI: NP_001171669.1, UniProt: Q14247 |
| Catalog # | MBS9704760 |
| Price | $130, $220, $325 |
| Order / More Info | Cortactin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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