BARD1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | BARD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total BARD1 protein. Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.Wu L.C., Nat. Genet. 14:430-440(1996).Thai T.H., Hum. Mol. Genet. 7:195-202(1998 |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human BARD1. |
| Other Names | [BRCA1-associated RING domain protein 1; BARD-1; BARD1] |
| Gene, Accession # | [BARD1], Gene ID: 580, NCBI: NP_000456.2, UniProt: Q99728 |
| Catalog # | MBS9410474 |
| Price | $200, $255 |
| Order / More Info | BARD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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