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Antigenic Specificity | [pSer15]HSP27 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, bovine, dog, guinea pig, monkey |
Isotype | n/a |
Format | Peptide Affinity purified |
Size | 0.05 mg, 0.2 mg |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, bovine, dog, guinea pig and monkey HSP27. Detects a band of ~27kDa by Western blot. Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 |
Immunogen | Immunogen: Synthetic peptide corresponding to a portion of human HSP27 phosphorylated at Ser15. |
Other Names | [HSP27], [HSPB1; HSPB1; CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102; HSP27; HSP28; HspB1; HSP 27; SRP27] |
Gene, Accession # | [HspB1; Heat shock protein 27], Gene ID: 3315, NCBI: P04792.2, UniProt: P04792 |
Catalog # | MBS565295 |
Price | $295, $545 |
Order / More Info | [pSer15]HSP27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |