[pSer15]HSP27 Antibody from MYBIOSOURCE INC.

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Antigenic Specificity[pSer15]HSP27
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, bovine, dog, guinea pig, monkey
Isotypen/a
FormatPeptide Affinity purified
Size0.05 mg, 0.2 mg
Concentrationn/a
ApplicationsImmunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionRecognizes human, bovine, dog, guinea pig and monkey HSP27. Detects a band of ~27kDa by Western blot. Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27
ImmunogenImmunogen: Synthetic peptide corresponding to a portion of human HSP27 phosphorylated at Ser15.
Other Names[HSP27], [HSPB1; HSPB1; CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102; HSP27; HSP28; HspB1; HSP 27; SRP27]
Gene, Accession #[HspB1; Heat shock protein 27], Gene ID: 3315, NCBI: P04792.2, UniProt: P04792
Catalog #MBS565295
Price$295, $545
Order / More Info[pSer15]HSP27 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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