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Antigenic Specificity | RDX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RDX antibody detects endogenous levels of total RDX. Function: Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.Subunit Structure: Binds SLC9A3R1 (PubMed:9430655). Interacts with NHERF1, NHERF2, LAYN, MME/NEP and ICAM2. Interacts with CPNE1 (via VWFA domain) and CPNE4 (via VWFA domain). Interacts with SPN and CD44 (By similarity).Post-translational Modifications: Phosphorylated by tyrosine-protein kinases. Phosphorylation by ROCK2 suppresses the head-to-tail association of the N-terminal and C-terminal halves resulting in an opened conformation which is capable of actin and membrane-binding (By similarity).Similarity: The N-terminal domain interacts with the C- |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Cytoplasm > Cytoskeleton. Cleavage furrow. Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (92%), Horse (100%), Sheep (92%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (1 |
Other Names | [CB567; CG12537; DFNB24; ESP10; Hh-induced MATH and BTB domain-containing protein; HIB; Moesin-B; Protein roadkill; RADI_HUMAN; Radixin; RDX] |
Gene, Accession # | [RDX], Gene ID: 5962, NCBI: NP_001247421.1, UniProt: P35241 |
Catalog # | MBS9605830 |
Price | $240, $280 |
Order / More Info | RDX Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |