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Antigenic Specificity | BMPR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BMPR2 antibody detects endogenous levels of total BMPR2. Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.Subunit Structure: Interacts with GDF5.Similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human BMPR2 Subcellular Location: Membrane. Tissue Specificity: Highly expressed in heart and liver. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (92%), Chicken (100%), Xenopus (100%) |
Other Names | [BMP type II receptor; BMP type-2 receptor; BMPR 2; BMPR 3; BMPR II; BMPR-2; BMPR-II; Bmpr2; BMPR2_HUMAN; BMPR3; BMPRII; BMR 2; BMR2; Bone morphogenetic protein receptor type 2; Bone morphogenetic protein receptor type II; Bone morphogenetic protein receptor type-2; Bone morphogenic protein receptor type II serine threonine kinase; BRK 3; BRK3; PPH 1; PPH1; Serine threonine kinase type II activin receptor like kinase; T ALK; TALK; Type II activin receptor like kinase] |
Gene, Accession # | [BMPR2], Gene ID: 659, NCBI: NP_001195.2, UniProt: Q13873 |
Catalog # | MBS9601555 |
Price | $240, $280 |
Order / More Info | BMPR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |