BMPR2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBMPR2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: BMPR2 antibody detects endogenous levels of total BMPR2. Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.Subunit Structure: Interacts with GDF5.Similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
ImmunogenImmunogen: A synthesized peptide derived from human BMPR2 Subcellular Location: Membrane. Tissue Specificity: Highly expressed in heart and liver. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (92%), Chicken (100%), Xenopus (100%)
Other Names[BMP type II receptor; BMP type-2 receptor; BMPR 2; BMPR 3; BMPR II; BMPR-2; BMPR-II; Bmpr2; BMPR2_HUMAN; BMPR3; BMPRII; BMR 2; BMR2; Bone morphogenetic protein receptor type 2; Bone morphogenetic protein receptor type II; Bone morphogenetic protein receptor type-2; Bone morphogenic protein receptor type II serine threonine kinase; BRK 3; BRK3; PPH 1; PPH1; Serine threonine kinase type II activin receptor like kinase; T ALK; TALK; Type II activin receptor like kinase]
Gene, Accession #[BMPR2], Gene ID: 659, NCBI: NP_001195.2, UniProt: Q13873
Catalog #MBS9601555
Price$240, $280
Order / More InfoBMPR2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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