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Antigenic Specificity | Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker) |
Clone | [KRT13/2213] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and |
Immunogen | Immunogen: Recombinant full-length human KRT13 protein |
Other Names | [CK13; Cytokeratin-13; Keratin Type I Cytoskeletal 13; Keratin-13; KRT13; Type I Cytoskeletal 13; WSN2] |
Gene, Accession # | [KRT13], Gene ID: 3860, NCBI: CAA36673.1, UniProt: P13646 |
Catalog # | MBS4381053 |
Price | $190, $340, $340 |
Order / More Info | Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Richard, G., et al. 1995. Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus. Nat. Genet. 11: 453-455. |