Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCytokeratin 13 (Non-Keratinized Squamous Epithelial Marker)
Clone[KRT13/2213]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and
ImmunogenImmunogen: Recombinant full-length human KRT13 protein
Other Names[CK13; Cytokeratin-13; Keratin Type I Cytoskeletal 13; Keratin-13; KRT13; Type I Cytoskeletal 13; WSN2]
Gene, Accession #[KRT13], Gene ID: 3860, NCBI: CAA36673.1, UniProt: P13646
Catalog #MBS4381053
Price$190, $340, $340
Order / More InfoCytokeratin 13 (Non-Keratinized Squamous Epithelial Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesRichard, G., et al. 1995. Keratin 13 point mutation underlies the hereditary mucosal epithelial disorder white sponge nevus. Nat. Genet. 11: 453-455.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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